Author

J. R. Mora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Das· 1 shared A. Mishra· 1 shared B. Geilich· 1 shared C. Mihai· 1 shared D. Alvarez· 1 shared G. Masse-Ranson· 1 shared J. Frederick· 1 shared J. Hoggatt· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Das

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2 papers

Recent·Most cited

Functional mRNA delivery to hematopoietic stem and progenitor cells in vivo.

D. Alvarez, G. Masse-Ranson, S. K. Sedimbi, P. Wisti, L. Rodriguez, J. Santana, T. Manning, T. Towner, B. Geilich, C. Mihai, A. Mishra, S. Gurumurthy, J. Frederick, U. H. von Andrian, J. Hoggatt, , J. R. Mora

This study demonstrates in vivo delivery of functional mRNA to hematopoietic stem cells (HSC) using lipid nanoparticles, achieving transfection in ~25% of mouse HSC with potential for therapeutic applications.

bioRxiv · Dec 15, 2022 · PreprintImmunology

A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ Treg differentiation

P. Mamontov, R. A. Eberwine, J. Perrigoue, A. Das, J. R. Friedman, J. R. Mora

This study shows that ITK knockdown increases Foxp3+ TREG differentiation and suppressive function in human T cells, suggesting ITK as a target to enhance TREGs in autoimmune diseases.

bioRxiv · Aug 7, 2018Immunology