Author

J. Rollin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Sarkar· 2 shared L. Rauova· 2 shared M. Poncz· 2 shared A. Bornert· 1 shared A. Mazharian· 1 shared C. Loubiere· 1 shared C. Vayne· 1 shared D. B. Cines· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

A. Sarkar

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2 papers

Recent·Most cited

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

A. Mazharian, O. Bertin, A. Sarkar, J. Augros, A. Bornert, C. Loubiere, F. Jönsson, J. Warwicker, W. M. Abbott, O. Dushek, C. Vayne, L. Rauova, K. Fütterer, J. Rollin, M. Poncz, Y. A. Senis

This study introduces CAPRIs, bispecific antibodies that inhibit platelet activation by clustering G6B with ITAM receptors, showing effectiveness in preventing thrombus formation without causing bleeding.

bioRxiv · May 10, 2024 · PreprintCell Biology

Prevention of thrombocytopenia and thrombosis in heparin-induced thrombocytopenia (HIT) using deglycosylated KKO: A novel therapeutic?

A. Sarkar, S. Khandelwal, H. Kim, Y. Gruel, J. Rollin, G. D. Wool, G. M. Arepally, D. B. Cines, L. Rauova, M. Poncz

This paper demonstrates that deglycosylated KKO (DGKKO) can prevent and reverse thrombocytopenia and thrombosis in a HIT murine model.

bioRxiv · Oct 19, 2022 · PreprintCell Biology