Author

W. M. Abbott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Mazharian· 2 shared C. Geh· 2 shared J. Warwicker· 2 shared K. Fütterer· 2 shared Y. A. Senis· 2 shared A. Bornert· 1 shared A. J. Barr· 1 shared A. Jouppila· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. Mazharian

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

A. Mazharian, O. Bertin, A. Sarkar, J. Augros, A. Bornert, C. Loubiere, F. Jönsson, J. Warwicker, W. M. Abbott, O. Dushek, C. Vayne, L. Rauova, K. Fütterer, J. Rollin, M. Poncz, Y. A. Senis

This study introduces CAPRIs, bispecific antibodies that inhibit platelet activation by clustering G6B with ITAM receptors, showing effectiveness in preventing thrombus formation without causing bleeding.

bioRxiv · May 10, 2024 · PreprintCell Biology

SARS-CoV-2 comprehensive receptor profiling: mechanistic insight to drive new therapeutic strategies

S. M. Brockbank, R. Faba-Rodriguez, L. Rosenbrier Ribeiro, C. Geh, H. Thomas, J. Delight, L. Coverley, W. M. Abbott, J. Soden, J. Freeth

The paper screens SARS-CoV-2 spike protein interactions with human cell surface receptors, identifying novel binding proteins and confirming known ones, to inform therapeutic strategies.

bioRxiv · Mar 11, 2021 · PreprintCell Biology

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

T. Vögtle, S. Sharma, J. Mori, Z. Nagy, D. Semeniak, M. J. Geer, C. W. Smith, J. Lane, S. Pollack, R. Lassila, A. Jouppila, A. J. Barr, D. J. Ogg, T. D. Howard, H. J. McMiken, , Y. A. Senis

This study identifies heparan sulfate as a critical regulator of G6b-B, showing it inhibits platelet and megakaryocyte function through Shp1/Shp2 signaling.

bioRxiv · Mar 25, 2019Biochemistry