Author

J. S. Brodbelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

J. N. Walker· 2 shared C. Jung· 1 shared C. L. McCafferty· 1 shared D. C. Wylie· 1 shared D. R. Klein· 1 shared D. W. Taylor· 1 shared E. A. Schwartz· 1 shared F. Guerin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

J. N. Walker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D CRISPR-Cas effector complex

E. A. Schwartz, J. P. Bravo, L. A. Macias, C. L. McCafferty, T. L. Dangerfield, J. N. Walker, J. S. Brodbelt, P. C. Fineran, R. D. Fagerlund, D. W. Taylor

The paper determines the structure of a type III-D CRISPR-Cas effector complex and characterizes its RNA cleavage mechanism, revealing how multi-subunit fusion proteins assemble into an active RNA endonuclease.

bioRxiv · Jun 13, 2022 · PreprintBiochemistry

Massively Parallel Selection of NanoCluster Beacons

Y.-A. Kuo, C. Jung, Y.-A. Chen, H.-C. Kuo, O. S. Zhao, T. D. Nguyen, J. R. Rybarski, S. Hong, Y.-I. Chen, D. C. Wylie, J. A. Hawkins, J. N. Walker, S. W. Shields, J. S. Brodbelt, J. T. Petty, , H.-C. Yeh

The paper develops a high-throughput method to screen and design multicolor NanoCluster Beacons using NGS chips and machine learning.

bioRxiv · Dec 4, 2021Bioengineering

Colistin heteroresistance in Enterobacter cloacae is mediated by PmrAB-independent 4-amino-4-deoxy-l-arabinose addition to lipid A

K. N. Kang, D. R. Klein, M. I. Kazi, F. Guerin, V. Cattoir, J. S. Brodbelt, J. M. Boll

This paper identifies a PmrAB-independent mechanism of colistin heteroresistance in Enterobacter cloacae involving PhoPQEcl-mediated addition of 4-amino-4-deoxy-l-arabinose to lipid A.

bioRxiv · Jan 11, 2019 · PreprintMicrobiology