Author

T. D. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 4 Cell Biology· 2 Evolutionary Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2

Frequent Co-Authors

H.-C. Yeh· 2 shared M. F. Boni· 2 shared M. Y. Lee· 2 shared P. Zorlutuna· 2 shared S. Hong· 2 shared T. N.-A. Tran· 2 shared Y.-A. Kuo· 2 shared Y.-I. Chen· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

H.-C. Yeh

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence

T. D. Nguyen, M. K. Rao, S. P. Dhyani, J. M. Banks, M. A. Winek, J. Michalkiewicz, M. Y. Lee

This study identifies Nup93 as a critical factor in maintaining endothelial cell health by preventing Yap nuclear accumulation and inflammation associated with aging.

bioRxiv · Nov 10, 2023Physiology

Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells

T. D. Nguyen, W. H. Chooi, H. Jeon, J. Chen, D. N. Roxby, J. Tan, C. Yi-Pin Lee, S.-Y. Ng, S. Y. Chew, J. Han

This study removes residual undifferentiated iPSCs from spinal-cord progenitor cells using size-based microfluidic separation, reducing OCT4-positive cells without affecting viability.

bioRxiv · Dec 16, 2022Bioengineering

Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparum

E. Z. Li, T. D. Nguyen, T. N.-A. Tran, R. J. Zupko, M. F. Boni

This study compares MFT and cycling policies for ACT deployment, finding MFT reduces multi-drug resistance risk by 4-90% in areas with ≥1% PfPR.

bioRxiv · May 31, 2022Evolutionary Biology

Endothelial Nitric Oxide Synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation

T. D. Nguyen, N.-T. Rahman, B. Sessa, M. Y. Lee

This study shows that phosphorylation of eNOS at S1176 by Akt determines atherosclerotic lesion formation, with phospho-mimic mutants reducing plaque while unphosphorylatable mutants increase it.

bioRxiv · Jan 13, 2022Physiology

Massively Parallel Selection of NanoCluster Beacons

Y.-A. Kuo, C. Jung, Y.-A. Chen, H.-C. Kuo, O. S. Zhao, T. D. Nguyen, J. R. Rybarski, S. Hong, Y.-I. Chen, D. C. Wylie, J. A. Hawkins, J. N. Walker, S. W. Shields, J. S. Brodbelt, J. T. Petty, , H.-C. Yeh

The paper develops a high-throughput method to screen and design multicolor NanoCluster Beacons using NGS chips and machine learning.

bioRxiv · Dec 4, 2021Bioengineering

General Finite-Element Framework of the Virtual Fields Method in Nonlinear Elasticity

Y. Mei, J. Liu, X. Guo, B. Zimmerman, T. D. Nguyen, S. Avril

This paper introduces a general finite-element framework for the Virtual Fields Method to identify constitutive parameters in nonlinear elasticity using measured deformation fields.

bioRxiv · May 10, 2021Bioengineering

Antimalarial mass drug administration in large populations and the evolution of drug resistance

T. D. Nguyen, T. N.-A. Tran, D. M. Parker, N. J. White, M. F. Boni

This study evaluates how mass drug administration (MDA) can accelerate drug resistance in large populations under specific conditions and highlights the importance of post-MDA case management.

bioRxiv · Mar 8, 2021Evolutionary Biology

Deep learning enables rapid and robust analysis of fluorescence lifetime imaging in photon-starved conditions

Y.-I. Chen, Y.-J. Chang, S.-C. Liao, T. D. Nguyen, J. Yang, Y.-A. Kuo, S. Hong, Y.-L. Liu, H. G. Rylander, S. R. Santacruz, T. E. Yankeelov, H.-C. Yeh

This paper introduces flimGANE, a deep learning method that rapidly and accurately generates FLIM images in low-photon conditions, outperforming traditional methods in speed and analysis accuracy.

bioRxiv · Dec 2, 2020 · PreprintCell Biology

Persistent cell motility requires transcriptional feedback of cytoskeletal - focal adhesion equilibrium by YAP/TAZ

D. E. Mason, J. H. Dawahare, T. D. Nguyen, Y. Lin, S. L. Voytik-Harbin, P. Zorlutuna, M. E. Yoder, J. D. Boerckel

The paper shows that YAP/TAZ transcriptional feedback is essential for maintaining cytoskeletal-focal adhesion equilibrium and persistent cell motility.

bioRxiv · May 30, 2018Cell Biology

An aged human heart tissue model showing age-related molecular and functional deterioration resembling the native heart

A. Acun, T. D. Nguyen, P. Zorlutuna

This paper develops an in vitro aged human heart tissue model using hiPSC-derived cardiomyocytes to study age-related molecular and functional deterioration in cardiovascular disease.

bioRxiv · Mar 22, 2018Bioengineering