Author

J. N. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. S. Brodbelt· 2 shared B. M. Hanson· 1 shared C. Jung· 1 shared C. L. McCafferty· 1 shared C. L. Obernuefemann· 1 shared D. C. Wylie· 1 shared D. W. Taylor· 1 shared E. A. Schwartz· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

J. S. Brodbelt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Defining the roles of pyruvate oxidation, TCA cycle, and mannitol metabolism in methicillin resistance Staphylococcus aureus urinary tract infection

R. Kulkarni, S. Paudel, S. Guedry, J. N. Walker, C. L. Obernuefemann, S. Hultgren

This paper identifies metabolic pathways critical for MRSA survival in urinary tract infections and suggests potential therapeutic targets.

bioRxiv · Oct 28, 2022 · PreprintMicrobiology

Staphylococcus aureus Breast Implant Infection Isolates Display Recalcitrance to Antibiotic Pocket Irrigants

J. M. Duran Ramirez, J. Gomez, B. M. Hanson, T. Isa, T. M. Myckatyn, J. N. Walker

This study evaluates the effectiveness of a triple antibiotic pocket irrigant (TAPI) against Staphylococcus aureus in breast implant infections, finding that while TAPI reduces infection in some strains, it promotes biofilm formation in others.

bioRxiv · Jul 18, 2022 · PreprintMicrobiology

Assembly of multi-subunit fusion proteins into the RNA-targeting type III-D CRISPR-Cas effector complex

E. A. Schwartz, J. P. Bravo, L. A. Macias, C. L. McCafferty, T. L. Dangerfield, J. N. Walker, J. S. Brodbelt, P. C. Fineran, R. D. Fagerlund, D. W. Taylor

The paper determines the structure of a type III-D CRISPR-Cas effector complex and characterizes its RNA cleavage mechanism, revealing how multi-subunit fusion proteins assemble into an active RNA endonuclease.

bioRxiv · Jun 13, 2022 · PreprintBiochemistry

Massively Parallel Selection of NanoCluster Beacons

Y.-A. Kuo, C. Jung, Y.-A. Chen, H.-C. Kuo, O. S. Zhao, T. D. Nguyen, J. R. Rybarski, S. Hong, Y.-I. Chen, D. C. Wylie, J. A. Hawkins, J. N. Walker, S. W. Shields, J. S. Brodbelt, J. T. Petty, , H.-C. Yeh

The paper develops a high-throughput method to screen and design multicolor NanoCluster Beacons using NGS chips and machine learning.

bioRxiv · Dec 4, 2021Bioengineering