Author

J. S. L. Yu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:yeast· 1

Frequent Co-Authors

A. Freiwald· 1 shared A. Zelezniak· 1 shared B. J. P. Huntly· 1 shared B. Papp· 1 shared C. B. Messner· 1 shared C. Correia-Melo· 1 shared E. De Braekeleer· 1 shared G. S. Vassiliou· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Freiwald

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan

C. Correia-Melo, S. Kamrad, C. B. Messner, R. Tengolics, L. Herrera-Dominguez, S. Townsend, M. T. Alam, A. Freiwald, K. Campbell, S. Aulakh, L. Szyrwiel, J. S. L. Yu, A. Zelezniak, V. Demichev, M. Muelleder, , M. Ralser

The paper shows that metabolite exchange between cells extends lifespan in yeast by creating a pro-survival metabolic environment.

bioRxiv · Mar 7, 2022Biochemistry

KAT7 is a therapeutic vulnerability of MLL-rearranged acute myeloid leukemia

Y. Z. Au, M. Gu, E. De Braekeleer, J. S. L. Yu, S. H. Ong, M. Gozdecka, X. Chen, K. Tzelepis, B. J. P. Huntly, G. S. Vassiliou, K. Yusa

This study identifies KAT7 as a critical therapeutic target in MLL-rearranged AML by showing its role in maintaining acetylation marks and supporting cell proliferation.

bioRxiv · Apr 25, 2020 · PreprintCancer Biology