Author

J. Schoggins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Majumdar· 1 shared A. Osinski· 1 shared C. Longoria· 1 shared C. Xing· 1 shared G. Hernandez· 1 shared G. J. Park· 1 shared H. Liang· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Kumar

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3 papers

Recent·Most cited

The mechanism of RNA capping by SARS-CoV-2

G. J. Park, A. Osinski, G. Hernandez, J. Eitson, A. Majumdar, M. Tonelli, K. Henzler-Wildman, K. Pawlowski, Z. Chen, Y. Li, J. Schoggins, V. S. Tagliabracci

This study reveals how SARS-CoV-2 caps its RNA genome through an unconventional mechanism involving RNAylation and methyltransferase activity, identifying potential antiviral targets.

bioRxiv · Feb 7, 2022Biochemistry

SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway

S. Khan, M. S. Shafiei, C. Longoria, J. Schoggins, R. C. Savani, H. Zaki

This study shows that SARS-CoV-2 spike protein induces inflammation in macrophages and epithelial cells via TLR2-dependent NF-κB activation, suggesting TLR2 as a therapeutic target for COVID-19.

bioRxiv · Mar 16, 2021Immunology

The IFN response in bat cells consists of canonical and non-canonical ISGs with unique temporal expression kinetics

P. C. De La Cruz-Rivera, M. Kanchwala, H. Liang, A. Kumar, L.-F. Wang, C. Xing, J. Schoggins

This study identifies canonical and non-canonical ISGs in bat cells with distinct temporal expression kinetics, revealing unique aspects of the IFN response that may contribute to viral resistance.

bioRxiv · Jul 24, 2017Immunology