J. Shaw

RAPID HEMATOCRIT ESTIMATION USING A FOLD-CREASE INDUCED FAST FLOWING PAPER SENSOR

This paper develops a fast-flowing paper sensor using fold-crease regions to estimate hematocrit efficiently with low cost and minimal sample volume.

Multi-omics discovery of hallmark protein and lipid features of circulating small extracellular vesicles in humans

The paper identifies hallmark protein and lipid features of circulating extracellular vesicles in humans using multi-omics analysis and provides an open-source tool for further exploration.

Intrauterine Growth-Restricted Pregnant Rats, from Hypertensive Placental Ischemic Dams Display Preeclamptic-like Symptoms: A New Rodent Model of Preeclampsia

This study establishes a new rodent model of preeclampsia by inducing intrauterine growth restriction in pregnant rats, showing elevated blood pressure and oxidative stress.

Physical constraints during Snowball Earth drive the evolution of multicellularity

The paper models how environmental changes during Snowball Earth glaciations created selective pressures that favored multicellularity in eukaryotes but not prokaryotes.

Climate Change Factors Interactively Shift Peatland Functional Microbial Composition in a Whole-Ecosystem Warming Experiment

The paper examines how temperature and CO2 interact to shift microbial functional composition in peatlands, showing size-dependent responses and potential impacts on carbon cycling.

Using image-based haplotype alignments to map global adaptation of SARS-CoV-2

This study uses image-based haplotype alignments to analyze SARS-CoV-2 evolution, finding increased fitness in the UK linked to specific viral lineages.

Impacts of intraspecific variability and local adaptation on the ecophysiology of mosses: an example with Sphagnum magellanicum

This study investigates whether intraspecific variability in Sphagnum magellanicum is due to phenotypic plasticity or local adaptation, finding that ecophysiological responses are largely plastic.

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

The paper designs a rationally derived inhibitor of HCV p7 channel activity, revealing its dual role in virus entry and infection spread, and highlights its potential for bimodal antiviral therapy.

Physiological regulation of bud burst in grapevine

This study investigates the physiological and biochemical mechanisms of bud burst in grapevine, showing that apoplastic pore size and oxygen status within the bud regulate the process without requiring long-distance signals.