Author

P. Meikle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Huynh· 2 shared A. Laskowski· 1 shared A. Rai· 1 shared A. Sanigorski· 1 shared B. Claridge· 1 shared B. Nijagal· 1 shared C. Bruce· 1 shared C. Duarte· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

K. Huynh

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Author profile →

3 papers

Recent·Most cited

Multi-omics discovery of hallmark protein and lipid features of circulating small extracellular vesicles in humans

A. Rai, K. Huynh, Q. H. Poh, H. Fang, B. Claridge, J. Cross, T. Duong, C. Duarte, J. Shaw, T. Marwick, P. Meikle, D. W. Greening

The paper identifies hallmark protein and lipid features of circulating extracellular vesicles in humans using multi-omics analysis and provides an open-source tool for further exploration.

bioRxiv · Mar 16, 2024Cell Biology

Deep multi-omic profiling reveals extensive mitochondrial remodeling driven by glycemia in early diabetic kidney disease

C. Granata, V. Thallas-Bonke, N. j. Caruana, K. Huynh, C. X. Qin, A. Laskowski, M. Snelson, J. Anthonisz, E. Jap, G. Ramm, M. E. Cooper, P. Meikle, D. A. Stroud, R. H. Ritchie, M. T. Coughlan

This study shows that blood glucose levels directly affect mitochondrial function and metabolism in early diabetic kidney disease, with changes in proteome, metabolome, and lipidome.

bioRxiv · Oct 26, 2023 · PreprintCell Biology

Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity

S. D. Martin, T. Connor, A. Sanigorski, K. A. McEwen, D. C. Henstridge, B. Nijagal, D. P. De Souza, D. Tull, P. Meikle, G. M. Kowalski, C. Bruce, P. Gregorevic, M. Febbraio, F. Collier, K. R. Walder, S. McGee

This study shows that HDAC4 and HDAC5 inhibit cell death pathways and protect muscle integrity by reducing oxidative metabolism and promoting survival under lipotoxic stress.

bioRxiv · Oct 17, 2022Cell Biology