Author

J. Skotheim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Organism:yeast· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

S. Zhang· 3 shared E. Zatulovskiy· 2 shared A. E. Ikui· 1 shared A. Rudner· 1 shared C. Curtis· 1 shared D. Chandler-Brown· 1 shared G. Q. G. de Medeiros· 1 shared J. Arand· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersCell Biology

S. Zhang

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5 papers

Recent·Most cited

The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size

S. Xie, S. Zhang, G. Q. G. de Medeiros, P. Liberali, J. Skotheim

This study shows that cell size autonomously regulates the G1/S transition in mammalian epidermal stem cells, independent of extracellular signals.

bioRxiv · Apr 9, 2024 · PreprintCell Biology

Whi5 hypo- and hyper- phosphorylation dynamics control cell cycle entry and progression

J. Y. Xiao, J. J. Turner, M. Koivomagi, J. Skotheim

This study identifies the phosphorylation sites on Whi5 and shows how their hypo- and hyper-phosphorylation regulate cell cycle entry and progression in budding yeast.

bioRxiv · Nov 2, 2023Cell Biology

The G1/S transition is promoted by Rb degradation via the E3 ligase UBR5

S. Zhang, L. F. Valenzuela, E. Zatulovskiy, L. F. S. Mangiante, C. Curtis, J. Skotheim

The paper identifies UBR5-mediated Rb degradation as a mechanism promoting G1/S transition by reducing Rb levels in early G1.

bioRxiv · Oct 3, 2023Cell Biology

The cell cycle inhibitor RB is diluted in G1 and contributes to controlling cell size in the mouse liver

S. Zhang, E. Zatulovskiy, J. Arand, J. Sage, J. Skotheim

This study shows that RB dilution during G1 phase controls cell size in mouse liver by linking cell growth to the G1/S transition.

bioRxiv · Jun 8, 2022Cell Biology

PP2ACdc55 dephosphorylates Pds1 to inhibit spindle elongation

S. Khondker, S. Kajjo, D. Chandler-Brown, J. Skotheim, A. Rudner, A. E. Ikui

The paper shows PP2ACdc55 dephosphorylates Pds1, disrupting its interaction with Esp1 to inhibit spindle elongation during replication stress.

bioRxiv · May 29, 2019 · PreprintCell Biology