Author

J. Stebbing

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Ditsiou· 1 shared A. R. Green· 1 shared D. L. Kontoyiannis· 1 shared E. A. Rakha· 1 shared E. Song· 1 shared F. M. G. Pearl· 1 shared G. Benstead-Hum· 1 shared G. Bresciani· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Ditsiou

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2 papers

Recent·Most cited

CRISPR screens in 3D tumourspheres identified miR-4787-3p as a transcriptional start site miRNA essential for breast tumour-initiating cell growth

T. Stiff, S. Bayraktar, P. Dama, J. Stebbing, L. Castellano

The paper identifies miR-4787-3p as an essential miRNA for breast tumor-initiating cell growth using CRISPR screens and validates its role as a potential therapeutic target and prognostic biomarker.

bioRxiv · Dec 6, 2023 · PreprintCell Biology

Global kinome silencing combined with 3D invasion screening of the tumor microenvironment identifies fibroblast-expressed PIK3Cδ involvement in triple-negative breast cancer progression

T. Gagliano, K. Shah, S. Gargani, L. Lao, M. Alsaleem, J. Chen, V. Ntafis, P. Huang, A. Ditsiou, V. Vella, K. Yadav, K. Bienkowska, G. Bresciani, K. Kang, L. Li, , G. Giamas

The paper identifies fibroblast-expressed PIK3Cδ as a key driver of triple-negative breast cancer progression through paracrine signaling and shows its prognostic significance.

bioRxiv · Nov 2, 2019 · PreprintCancer Biology