ITGB6 inhibition stimulates anti-tumor responses in immunocompetent mouse models of head & neck squamous cell carcinoma and pancreatic adenocarcinoma
W. J. MacDonald, P. R. Srinivasan, M. Pinho-Schwermann, S. Zhang, V. Tajiknia, C. Purcell, J. Strandberg, W. S. El-Deiry
This study shows that inhibiting ITGB6 enhances anti-tumor immune responses in mouse models of head and neck and pancreatic cancers, with potential for combination immunotherapy.
bioRxiv · Apr 18, 2024 · PreprintCancer Biology