W. Weber

The prion-like domain of the chloroplast RNA binding protein CP29A is required for cold-induced phase separation next to nucleoids and supports RNA splicing and translation during cold acclimation

This study shows that the prion-like domain of CP29A enables temperature-dependent phase separation in Arabidopsis, supporting RNA splicing and translation during cold acclimation.

Real-time monitoring of cell surface protein arrival with split luciferases

This paper introduces a method using split luciferases to monitor real-time arrival of cell surface proteins in live cells with single-cell sensitivity.

SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner

This study shows that HilD activation in Salmonella Typhimurium reduces motility via SPI-1-dependent PMF depletion and adhesin upregulation, enhancing adhesion to host cells.

A MAD7-based genome editing system for E. coli

The paper develops a MAD7-based genome editing system for E. coli to efficiently generate SNPs and gene deletions, demonstrating its utility in industrial strain engineering.

Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands

This study shows that breast cancer stem cells escape γδ T cell immunosurveillance by losing key ligands and antigens, and that this escape can be reversed with Zoledronate or IFN- treatment.

Remorin proteins serve as membrane topology scaffolds in plants

The paper shows remorin proteins stabilize membrane tubules and curvature during symbiotic infections in plants.

OptoAssay - Light-controlled Dynamic Bioassay Using Optogenetic Switches

The paper introduces OptoAssay, a light-controlled bioassay that enables bidirectional movement of components using optogenetic switches, eliminating the need for pumps, valves, and external readout devices.

Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor

The study shows that the half-life of the ligand-T cell receptor complex determines T cell activation, supporting the kinetic proofreading model.