Author

L. Newman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Awuah· 2 shared B. Stonaker· 2 shared E. B. Osei-Bonsu· 2 shared E. Cheng· 2 shared E. K. Adjei· 2 shared F. S. Aitpillah· 2 shared I. Kyei· 2 shared J. K. Oppong· 2 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

B. Awuah

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Kinome focused CRISPR-Cas9 screens in African ancestry patient-derived breast cancer organoids identifies essential kinases and synergy of EGFR and FGFR1 inhibition.

F. P. Madorsky Rowdo, R. Martini, S. E. Ackermann, C. P. Tang, M. Tranquile, A. Irizarry, I. Us, O. Alawa, J. E. Moyer, M. Sigouros, J. Nguyen, M. A. Assaad, E. Cheng, P. S. Ginter, J. Manohar, , M. L. Martin

The paper uses CRISPR-Cas9 screens in breast cancer organoids from African ancestry patients to identify essential kinases and show synergy between EGFR and FGFR1 inhibitors.

Cancer Research · Feb 1, 2025Peer-reviewedCancer Biology

Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment

F. P. M. Rowdo, G. Xiao, G. F. Khramtsova, J. Nguyen, O. Olopade, R. Martini, B. Stonaker, R. Boateng, J. K. Oppong, E. K. Adjei, B. Awuah, I. Kyei, F. S. Aitpillah, M. O. Adinku, K. Ankomah, , J. Bargonetti

This study shows that tumor organoids with mutant p53 are more sensitive to the combination of PARP inhibitor and temozolomide than those with wild-type p53.

bioRxiv · Jun 22, 2023Cancer Biology

The biology of aging in a social world: insights from free-ranging rhesus macaques

L. Newman, C. Testard, A. R. DeCasien, K. L. Chiou, M. M. Watowich, M. C. Janiak, M. A. Pavez-Fox, M. R. Sanchez Rosado, E. B. Cooper, C. E. Costa, R. M. Petersen, M. M. Montague, M. L. Platt, L. J. N. Brent, N. Snyder-Mackler, J. P. Higham

This paper reviews how social adversity affects aging in rhesus macaques, focusing on ecological and social factors and the impact of Hurricane Maria.

bioRxiv · Jan 28, 2023Immunology

A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild-derived and classical inbred mouse strains

C. T. Watson, J. T. Kos, W. S. Gibson, C. E. Busse, L. Newman, G. Deikus, M. L. Smith, K. J. Jackson, A. M. Colins

The paper compares immunoglobulin gene diversity in wild-derived and classical inbred mouse strains, finding novel alleles and highlighting genetic complexity in IGH loci.

bioRxiv · Aug 7, 2019Immunology