Author

J. T. Webber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Gordan· 2 shared R. S. Levin· 2 shared S. Bandyopadhyay· 2 shared A. Choi· 1 shared A. Goga· 1 shared A. Pitea· 1 shared D. Swaney· 1 shared E. McCarthy· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

J. Gordan

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Author profile →

2 papers

Recent·Most cited

HBV rewires liver cancer signaling by altering PP2A complexes

A. Pitea, R. Turnham, M. Eckhardt, G. M. Jang, Z. Xu, H. C. Lim, A. Choi, J. Von Dollen, R. S. Levin, J. T. Webber, E. McCarthy, J. Hu, X. Li, L. Che, G. Chan, , J. Gordan

This study identifies how HBV alters PP2A complexes to drive liver cancer signaling, revealing potential therapeutic targets.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Kinome rewiring reveals AURKA is a molecular barrier to the efficacy of PI3K/mTOR-pathway inhibitors in breast cancer

H. J. Donnella, J. T. Webber, R. S. Levin, R. Camarda, O. Momcilovic, N. Bayani, K. N. Shah, J. Korkola, K. M. Shokat, A. Goga, J. Gordan, S. Bandyopadhyay

The paper identifies AURKA as a barrier to PI3K/mTOR inhibitor efficacy in breast cancer by mapping kinome dynamics and showing that AURKA inhibition synergizes with these drugs to induce apoptosis and tumor regression.

bioRxiv · Jun 30, 2017Cancer Biology