Author

J. T.-S. Chow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

I. Jurisica· 2 shared L. Salmena· 2 shared M. Kotlyar· 2 shared M. M. Gabra· 2 shared A. He· 1 shared A. Rashid· 1 shared C. A. Newell· 1 shared C. J. Guidos· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

I. Jurisica

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2 papers

Recent·Most cited

INPP4B drives lysosome biogenesis to restrict leukemic stem cell differentiation and promote leukemogenesis

J. F. Woolley, K. Chen, G. T. Saffi, G. E. Genc, D. K. C. Lee, I. Dzneladze, R. He, J. T.-S. Chow, M. M. Gabra, M. H. Son, C. M. P. Melo, C. A. Newell, A. He, E. M. Schoof, S. Z. Xie, , L. Salmena

This study identifies INPP4B's role in promoting leukemic stem cell (LSC) survival by enhancing lysosome biogenesis, leading to poor AML prognosis and suggesting therapeutic targets.

bioRxiv · Mar 25, 2021 · PreprintCancer Biology

Essential gene networks in acute myeloid leukemia identified using a microRNA-knockout CRISPR library screen

M. M. Gabra, C. Pastrello, N. Machado, J. T.-S. Chow, M. Kotlyar, T. Tokar, I. Jurisica, L. Salmena

The paper identifies essential miRNAs and their target genes in AML using a CRISPR screen and pathway analysis.

bioRxiv · Jun 6, 2019 · PreprintCancer Biology