Author

D. Matthews

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

K. Sawmynaden· 2 shared A. Davidson· 1 shared A. Javed· 1 shared A. Karatt-Vellatt· 1 shared A. M. Damry· 1 shared A. Oleksy· 1 shared B. Lee· 1 shared B. M. Lee· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

K. Sawmynaden

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

V. Vongsouthi, R. Georgelin, D. Matthews, J. Saunders, B. M. Lee, J. Ton, A. M. Damry, R. Frkic, M. A. Spence, C. J. Jackson

This study uses ancestral sequence reconstruction to explore PET-degrading cutinase sequence space, revealing diverse evolutionary pathways and the effectiveness of LASE in mapping fitness landscapes.

bioRxiv · Apr 25, 2024Biochemistry

TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

H. Khan, H. Winstone, J. Jimenez-Guardeno, C. Graham, K. Doores, C. Goujon, D. Matthews, A. Davidson, S. Rihn, M. Palmarini, S. Neil, M. Malim

This study shows that NCOA7 restricts SARS-CoV-2 infection by promoting endosomal acidification, and TMPRSS2 or removal of the furin cleavage site reduces this restriction.

bioRxiv · Jul 23, 2021Microbiology

Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence

G. Bullen, J. D. Galson, P. Villar, L. Moreels, L. Ledsgaard, G. Mattiuzzo, G. Hall, E. M. Bentley, E. W. Masters, D. Tang, S. Millett, D. Tongue, R. Brown, I. Diamantopoulos, K. Parthiban, , A. Karatt-Vellatt

The paper identifies potent neutralising antibodies from early COVID-19 patient samples and shows high convergence in antibody sequences across studies.

bioRxiv · Dec 29, 2020 · PreprintImmunology

Mechanochemical control of epidermal stem cell divisions by B-plexins

C. Jiang, A. Javed, L. Kaiser, M. M. Nava, D. Zhao, D. T. Brandt, J. Fernandez-Baldovinos, L. Zhou, C. Hoess, K. Sawmynaden, A. Oleksy, D. Matthews, L. S. Weinstein, H.-J. Groene, C. M. Niessen, , T. Worzfeld

This study identifies B-plexins as critical for mechanosensing in epidermal stem cells, linking mechanical feedback to cell division control during development and in cancer.

bioRxiv · Apr 30, 2020Cell Biology

Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK-cell activity

F. M. Lum, D. Lee, T.-K. Chua, J. J. Tan, C. Y. Lee, X. Liu, Y. Fang, B. Lee, W.-X. Yee, N. Rickett, P.-Y. Chia, V. Lim, Y.-S. Leo, D. Matthews, J. Hiscox, L. F. Ng

This study investigates how ZIKV infection affects monocyte and NK-cell activity through transcriptomic and immunoproteomic analyses, revealing counterbalancing effects on immune responses.

bioRxiv · Dec 5, 2017Immunology