Author

J. van der Velden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. C. Rankin· 1 shared A. Main· 1 shared A. Shemesh· 1 shared A.-P. Papageorgiou· 1 shared B. Geertz· 1 shared B. L. Prosser· 1 shared C. Y. Chen· 1 shared D. Lindner· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. C. Rankin

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Author profile →

4 papers

Recent·Most cited

Ribosomal Protein SA (RPSA) is required for localized translation and sarcomere maintenance in mice

R. Haddad, O. Sadeh, T. Ziv, I. Erlich, L. Haimovich-Caspi, A. Shemesh, J. van der Velden, I. Kehat

This study shows RPSA is necessary for ribosome localization to Z-lines and local translation, which supports sarcomere maintenance in mice.

bioRxiv · Jul 26, 2023 · PreprintCell Biology

Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function

N. Pietsch, C. Y. Chen, S. Kupsch, L. Bacmeister, B. Geertz, M. Herera-Rivero, H. Voss, E. Krämer, I. Braren, D. Westermann, H. Schlüter, G. Mearini, S. Schlossarek, J. van der Velden, M. A. Caporizzo, , L. Carrier

bioRxiv · May 25, 2023Physiology

Cardiac myosin binding protein-C palmitoylation is associated with increased myofilament affinity, reduced myofilament Ca2+ sensitivity and is increased in ischaemic heart failure.

A. Main, G. N. Milburn, R. M. Balesar, A. C. Rankin, G. L. Smith, K. Campbell, G. S. Baillie, J. van der Velden, W. Fuller

This study identifies palmitoylation of cMyBP-C in cardiac myofilaments, showing it reduces Ca2+ sensitivity and is altered in heart failure.

bioRxiv · Jun 21, 2022 · PreprintCell Biology

Extracellular SPARC improves cardiomyocyte contraction during health and disease

S. Deckx, D. M. Johnson, M. Rienks, P. Carai, E. van Deel, J. van der Velden, K. Sipido, S. Heymans, A.-P. Papageorgiou

This study shows extracellular SPARC enhances cardiomyocyte contraction in both healthy and diseased hearts, with potential therapeutic implications for myocarditis-related cardiac dysfunction.

bioRxiv · Dec 12, 2018Physiology