Author

C. Y. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. G. Henssen· 2 shared M. A. Caporizzo· 2 shared A. Eggert· 1 shared A. K. Salomon· 1 shared A. Lissat· 1 shared A. M. Wengner· 1 shared B. D. Henriksbo· 1 shared B. Geertz· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

A. G. Henssen

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Author profile →

5 papers

Recent·Most cited

Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function

N. Pietsch, C. Y. Chen, S. Kupsch, L. Bacmeister, B. Geertz, M. Herera-Rivero, H. Voss, E. Krämer, I. Braren, D. Westermann, H. Schlüter, G. Mearini, S. Schlossarek, J. van der Velden, M. A. Caporizzo, , L. Carrier

bioRxiv · May 25, 2023Physiology

Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers

J. T. Lange, C. Y. Chen, Y. Pichugin, F. Xie, J. Tang, K. L. Hung, K. E. Yost, Q. Shi, M. L. Erb, U. Rajkumar, S. Wu, C. Swanton, Z. Liu, W. Huang, H. Y. Chang, , P. S. Mischel

bioRxiv · Jun 11, 2021 · PreprintCancer Biology

Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy

H. Dorado Garcia, Y. Bei, J. von Stebut, G. Ibanez, K. Imami, D. Gurgen, J. Rolff, K. Helmsauer, N. Timme, V. Bardinet, R. Chamorro Gonzalez, I. C. MacArthur, F. F. Pusch, C. Y. Chen, J. Schulz, , A. G. Henssen

This study identifies ATR as a synthetic lethal target in PAX3-FOXO1-driven rhabdomyosarcoma, showing ATR inhibition enhances PARP inhibitor efficacy and is tolerated in patients.

bioRxiv · Dec 4, 2020 · PreprintCancer Biology

Gut microbiota impairs insulin clearance during obesity

K. P. Foley, S. Zlitni, B. M. Duggan, N. Barra, F. F. Anhe, J. F. Cavallari, B. D. Henriksbo, C. Y. Chen, M. Huang, T. Lau, J. D. Schertzer

This study shows that gut microbiota impair insulin clearance during obesity, with specific bacterial taxa linked to this effect, suggesting potential therapeutic targets.

bioRxiv · May 8, 2020 · PreprintPhysiology

Microtubules provide a viscoelastic resistance to myocyte motion.

M. A. Caporizzo, C. Y. Chen, A. K. Salomon, K. Bedi, K. B. Margulies, B. Prosser

This study investigates the mechanical role of microtubules in myocytes, finding they provide viscoelastic resistance that affects contraction and relaxation.

bioRxiv · Jul 3, 2018Biophysics