Author

J. Vielmetter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Escolano· 1 shared A. W. Lam· 1 shared D. Brown· 1 shared D. Goertsen· 1 shared E. E. Sullivan· 1 shared H. B. Gristick· 1 shared J. A. Baccile· 1 shared J. R. Keeffe· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Escolano

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Author profile →

3 papers

Recent·Most cited

Engineering antigen-specific tolerance to an artificial protein hydrogel

P. B. Rapp, J. A. Baccile, R. P. Galimidi, J. Vielmetter

This study engineers artificial protein hydrogels to induce antigen-specific tolerance, showing that non-self gels elicit stronger immune responses than self gels, which can be suppressed by targeting epitopes.

ACS Biomaterials Science & Engineering · Mar 13, 2024Peer-reviewedBioengineering

Primate-conserved Carbonic Anhydrase IV and murine-restricted Ly6c1 are new targets for crossing the blood-brain barrier

T. F. Shay, E. E. Sullivan, X. Ding, X. Chen, S. R. Kumar, D. Goertsen, D. Brown, J. Vielmetter, M. Borsos, A. W. Lam, V. Gradinaru

The paper identifies two new receptors, Ly6c1 and Car4/CA4, for crossing the blood-brain barrier using AAV vectors and computational modeling.

bioRxiv · Jan 12, 2023Bioengineering

Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope

M. E. Abernathy, H. B. Gristick, J. Vielmetter, J. R. Keeffe, P. N. Gnanapragasam, Y. E. Lee, A. Escolano, R. Gautam, M. S. Seaman, M. A. Martin, M. C. Nussenzweig, P. J. Bjorkman

This study identifies an off-target antibody that displaces the HIV-1 Env fusion peptide and blocks neutralizing epitopes, providing insights for vaccine design.

bioRxiv · Mar 17, 2021Immunology