Author

J. W. Kwak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. J. Neuwelt· 2 shared A. M. Johnson· 2 shared B. L. Bullock· 2 shared E. T. Clambey· 2 shared H. Y. Li· 2 shared J. M. Poczobutt· 2 shared K. Hopp· 2 shared R. A. Nemenoff· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. J. Neuwelt

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2 papers

Recent·Most cited

Cancer Cell Intrinsic Expression of MHCII Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma

A. M. Johnson, B. L. Bullock, A. J. Neuwelt, J. M. Poczobutt, R. E. Kaspar, H. Y. Li, J. W. Kwak, K. Hopp, M. C. M. Weiser-Evans, L. E. Heasley, E. L. Schenk, E. T. Clambey, R. A. Nemenoff

This study shows that cancer cell expression of MHCII affects T cell infiltration and response to anti-PD-1 therapy in lung adenocarcinoma.

bioRxiv · Jan 9, 2020 · PreprintCancer Biology

Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC

B. L. Bullock, A. K. Kimball, J. M. Poczobutt, H. Y. Li, J. W. Kwak, A. J. Neuwelt, A. M. Johnson, E. Kleczko, R. Kaspar, K. Hopp, E. Schenk, M. C. Weiser-Evans, E. T. Clambey, R. A. Nemenoff

This study identifies tumor-intrinsic IFN-gamma signaling as a determinant of anti-PD-1 response in NSCLC by altering the tumor microenvironment.

bioRxiv · Jan 27, 2019Cancer Biology