Author

R. E. Kaspar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

E. T. Clambey· 4 shared A. K. Kimball· 3 shared L. F. van Dyk· 3 shared L. M. Oko· 3 shared A. C. Nelson· 1 shared A. J. Neuwelt· 1 shared A. M. Johnson· 1 shared A. N. Knox· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersMicrobiology

E. T. Clambey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Receptor for Hyaluronan-Mediated Motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients.

S. E. Tarullo, Y. He, C. Daughters, T. P. Knutson, C. Henzler, M. Price, R. Shanley, P. Witschen, C. Tolg, R. E. Kaspar, C. Hallstrom, L. Gittsovich, M. L. Sulciner, X. Zhang, C. Forester, , A. C. Nelson

This study identifies RHAMM as a marker of invasive niches in breast cancer, showing its association with poor outcomes and promoting invasion through a 27-gene signature.

bioRxiv · Jun 13, 2022Cancer Biology

Redefining De Novo Gammaherpesvirus Infection Through High-Dimensional, Single-Cell Analysis of Virus and Host

J. N. Berger, B. Sanford, A. K. Kimball, L. M. Oko, R. E. Kaspar, B. F. Niemeyer, K. L. Jones, E. T. Clambey, L. F. van Dyk

This paper uses single-cell RNA sequencing and mass cytometry to analyze variation in viral and host gene expression during de novo gammaherpesvirus infection.

bioRxiv · Aug 11, 2020 · PreprintMicrobiology

Cancer Cell Intrinsic Expression of MHCII Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma

A. M. Johnson, B. L. Bullock, A. J. Neuwelt, J. M. Poczobutt, R. E. Kaspar, H. Y. Li, J. W. Kwak, K. Hopp, M. C. M. Weiser-Evans, L. E. Heasley, E. L. Schenk, E. T. Clambey, R. A. Nemenoff

This study shows that cancer cell expression of MHCII affects T cell infiltration and response to anti-PD-1 therapy in lung adenocarcinoma.

bioRxiv · Jan 9, 2020 · PreprintCancer Biology

Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression

L. M. Oko, A. K. Kimball, R. E. Kaspar, A. N. Knox, C. B. Coleman, R. Rochford, T. Chang, B. Alderete, L. F. van Dyk, E. T. Clambey

This paper uses single-cell analysis to reveal heterogeneity in gammaherpesvirus gene expression across different infection stages.

bioRxiv · Apr 11, 2019Microbiology

High-dimensional characterization of IL-10 production and IL-10 dependent regulation during primary gammaherpesvirus infection

A. K. Kimball, L. M. Oko, R. E. Kaspar, L. F. van Dyk, E. T. Clambey

This paper investigates IL-10 production and its regulatory role during primary gammaherpesvirus infection using high-dimensional analysis in mice.

ImmunoHorizons · Mar 22, 2019Peer-reviewedImmunology