J. Wittbrodt

Characterizing medaka visual features using a high-throughput optomotor response assay

This study develops a high-throughput optomotor response assay in medaka larvae to quantify visual traits and detect strain-specific differences.

Minimal-invasive 3D laser printing of microimplants in organismo

The paper presents a platform for minimal-invasive 3D laser printing of microimplants in vivo using synthetic polymer inks, demonstrating biological responses in teleost fish and fruit fly embryos.

DNA microbeads for spatio-temporally controlled morphogen release within organoids

This paper introduces DNA microbeads to control morphogen release in organoids, enabling spatio-temporal regulation of development and improving tissue mimicry.

2-photon laser printing to mechanically stimulate multicellular systems in 3D

This paper develops a 2-photon printing method to create 3D microstructures for mechanically stimulating multicellular systems, showing cells change morphology under cyclic stretch.

Deep learning-enhanced light-field imaging with continuous validation

This paper introduces a deep learning framework for light-field microscopy that uses continuous validation during image reconstruction, achieving high-quality video-rate reconstructions of medaka heart dynamics and zebrafish neural activity.

Instantaneous isotropic volumetric imaging of fast biological processes

This paper introduces a method for high-speed, isotropic 3D imaging of biological processes with single-cell resolution and minimal motion artefacts.

Dynamics of ASC speck formation during skin inflammatory responses in vivo

The paper uses a live ASC reporter in zebrafish to study speck formation and pyroptosis in skin inflammation.