R. Prevedel

An interplay of HSP-proteostasis, biomechanics and ECM-cell junctions ensures C. elegans astroglial architecture

The paper identifies how HSP-proteostasis, biomechanics, and ECM-cell junctions interact to maintain C. elegans astroglial architecture across aging.

Deep intravital brain tumor imaging enabled by tailored three-photon microscopy and analysis

This paper introduces Deep3P, a three-photon microscopy and AI analysis method that enables deep intravital imaging of glioblastoma in mouse brains, revealing new insights into tumor invasion routes and white matter disruption.

Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens

This paper introduces pulsed stimulated Brillouin microscopy to improve mechanical imaging of live biological specimens with reduced phototoxicity and enhanced signal-to-background ratio.

An oblique plane microscope for mesoscopic imaging of freely moving organisms with cellular resolution

This paper introduces a mesoscopic oblique plane microscope capable of imaging freely moving organisms at cellular resolution, demonstrating its use on sea anemones.

High-resolution line-scan Brillouin microscopy for live-imaging of mechanical properties during embryo development

This paper introduces a high-resolution line-scan Brillouin microscope for live-imaging mechanical properties during embryo development with reduced photo-toxicity.

Mechanical mapping of mammalian follicle development using Brillouin microscopy

This study uses Brillouin microscopy to quantify mechanical properties of mouse ovarian tissues during follicle development, revealing distinct material properties and intra-follicular compartments.

Adaptive optics enhanced all-optical photoacoustic tomography

This paper introduces an adaptive optics method to enhance photoacoustic sensor sensitivity and image quality in vivo.

High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy

This paper develops a method for high-resolution deep brain imaging in mice using adaptive optics three-photon microscopy and demonstrates its ability to image deep cortical structures and astrocyte calcium transients.

In-vivo monitoring and quantification of breast cancer growth dynamics with non-invasive intravital mesoscopic fluorescence molecular tomography

This study introduces a non-invasive imaging method to quantitatively track tumor growth in living mice, finding that tumor volume is not well correlated with cell quantity.

Deep learning-enhanced light-field imaging with continuous validation

This paper introduces a deep learning framework for light-field microscopy that uses continuous validation during image reconstruction, achieving high-quality video-rate reconstructions of medaka heart dynamics and zebrafish neural activity.

Imaging mechanical properties of sub-micron ECM in live zebrafish using Brillouin microscopy

This study uses Brillouin microscopy to measure the thickness and mechanical properties of the ECM in live zebrafish, finding it to be ~400nm thick.

Instantaneous isotropic volumetric imaging of fast biological processes

This paper introduces a method for high-speed, isotropic 3D imaging of biological processes with single-cell resolution and minimal motion artefacts.