Author

J. Wyckoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. P. Straehla· 2 shared P. T. Hammond· 2 shared A. J. Pickering· 1 shared A. N. Lau· 1 shared C. Hajal· 1 shared G. Offeddu· 1 shared H. C. Safford· 1 shared L. Florek· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

J. P. Straehla

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Core material and surface chemistry of Layer-by-Layer (LbL) nanoparticles independently direct uptake, transport, and trafficking in preclinical blood-brain barrier (BBB) models

N. G. Lamson, A. J. Pickering, J. Wyckoff, P. Ganesh, J. P. Straehla, P. T. Hammond

This study shows that nanoparticle core stiffness and surface chemistry independently affect uptake, transport, and trafficking across the blood-brain barrier in vitro and in vivo.

bioRxiv · Oct 31, 2022 · PreprintBioengineering

A predictive microfluidic model of human glioblastoma to assess trafficking of blood-brain barrier penetrant nanoparticles

J. P. Straehla, C. Hajal, H. C. Safford, G. Offeddu, N. Boehnke, T. Dacoba, J. Wyckoff, R. D. Kamm, P. T. Hammond

This paper develops a microfluidic model of human glioblastoma to study nanoparticle trafficking across the blood-brain barrier and evaluates their therapeutic efficacy.

bioRxiv · Dec 7, 2021Bioengineering

Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors

R. Datta, A. N. Lau, S. Sivanand, L. Florek, J. Wyckoff, M. C. Skala, M. G. Vander Heiden

The paper investigates how interactions with pancreatic stromal cells affect the redox state of cancer cells, finding that these interactions promote a more oxidized redox state in cancer cells.

bioRxiv · Oct 20, 2020Cancer Biology