Aglycone polyether ionophores as broad-spectrum agents inhibit multiple enveloped viruses including SARS-CoV-2 in vitro and successfully cure JEV infected mice
T. Liu, J.-Q. Li, M. Huang, Y.-N. Zhang, R. Liu, Z.-R. Zhang, Q.-Y. Zhang, Y. Wang, J. Liu, Z. Deng, B. Zhang, H.-Q. Ye
This study identifies aglycone polyether ionophores as broad-spectrum antivirals effective against multiple enveloped viruses, including SARS-CoV-2, and demonstrates their efficacy in curing JEV-infected mice.
bioRxiv · Oct 27, 2020 · PreprintMicrobiology