Author

Jaasiel Alvarez

California Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Chengcheng FaniD· 2 shared Han GaoiD· 2 shared Jennifer R. KeeffeiD· 2 shared Kathryn E. MalecekiD· 2 shared Luisa N. SegoviaiD· 2 shared Pamela J. BjörkmaniD· 2 shared Priyanthi N.P. GnanapragasamiD· 2 shared Semi RhoiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

Chengcheng FanORCID

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Author profile →

3 papers

Recent·Most cited

A mosaic RBD-nanoparticle pan-sarbecovirus vaccine elicits nanobodies that target highly conserved epitopes

Kathryn E. Malecek, Jennifer R. Keeffe, Chengcheng Fan, Jaasiel Alvarez, Alyssa Player, Han Gao, Priyanthi N.P. Gnanapragasam, Semi Rho, Lisa M. Schimanski, Luisa N. Segovia, Tiong Kit Tan, Pamela J. Björkman

This study identifies nanobodies targeting conserved SARS-CoV-2 RBD epitopes that neutralize variants and zoonotic sarbecoviruses.

bioRxiv · Oct 15, 2026 · PreprintImmunology

Impact of sex and glial tau expression on heat shock protein induction in a Drosophila model of tauopathy

Marguerite Whitmore, Maeve Louise Coughlan, Martha A. Kahlson, Jaasiel Alvarez, Louisa Zebrowski, Kenneth J. Colodner, Kathryn A. McMenimen

This study examines how sex and glial tau expression affect heat shock protein induction in a Drosophila tauopathy model, finding sexually dimorphic Hsp expression and tau-induced disruption of Hsp induction.

ACS Omega · Sep 25, 2025Peer-reviewedNeuroscience

Cross-reactive sarbecovirus antibodies induced by mosaic RBD-nanoparticles

Chengcheng Fan, Jennifer R. Keeffe, Kathryn E. Malecek, Alexander A. Cohen, Anthony P. West, Viren A. Baharani, Annie V. Rorick, Han Gao, Priyanthi N.P. Gnanapragasam, Semi Rho, Jaasiel Alvarez, Luisa N. Segovia, Théodora Hatziioannou, Paul D. Bieniasz, Pamela J. Björkman

This paper develops mosaic RBD-nanoparticles to induce cross-reactive anti-sarbecovirus antibodies in animals, demonstrating their effectiveness against SARS-CoV-2 variants and zoonotic viruses.

Proceedings of the National Academy of Sciences · May 22, 2025Peer-reviewedImmunology