Author

Jacob Icardi

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:imaging· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:spatial domain detection· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Hod DanaiD· 4 shared Aniruddha DasiD· 3 shared Julie A. BorovickaiD· 3 shared Ghazaal TahmasebiiD· 2 shared Hale TobiniD· 2 shared Jacob RaberiD· 2 shared Priyanka Agochiya· 2 shared Sarah J. Holden· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Hod DanaORCID

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Author profile →

4 papers

Recent·Most cited

Early Increases in Hippocampal Synchrony Predict Chronic Epileptiform Burden in a Temporal Lobe Epilepsy Model

Nadia Gasmi, Hale Tobin, Delnia Ahmadpour, Ghazaal Tahmasebi, Amirhossein Koohfar, Sam Kalnitsky, Morgan Rogers-Carter, Jacob Icardi, Sarah Roehrs, Sierra Bhatia, Hannah Shindler, Jordon Manworren, Priyanka Agochiya, Shriya Singh, Sarah Stanko, , Dimitrios Davalos

bioRxiv · Nov 5, 2026 · PreprintNeuroscience

Remyelinating therapy reverses neuronal activity suppression in a mouse model of demyelination

Aniruddha Das, Julie A. Borovicka, Hale Tobin, Rajaram Kshetri, Shruti Bhatia, Jacob Icardi, Ghazaal Tahmasebi, Priyanka Agochiya, Shriya Singh, Jordon Manworren, Philopater Isak, Willow Lev, Bruce D. Trapp, Tara M. DeSilva, Hod Dana

This study shows that remyelinating therapy with clemastine restores neuronal activity in a mouse model of demyelination, with sex-dependent recovery patterns.

bioRxiv · Feb 3, 2025 · PreprintNeuroscience

Systemic exposure to COVID-19 virus-like particles modulates firing patterns of cortical neurons in the living mouse brain

Aniruddha Das, Jacob Icardi, Julie A. Borovicka, Sarah J. Holden, Henry F. Harrison, Alec J. Hirsch, Jacob Raber, Hod Dana

This study shows that systemic exposure to SARS-CoV-2 virus-like particles disrupts cortical neuronal activity in mice, with persistent effects and heightened vulnerability in htau mice.

bioRxiv · Nov 26, 2024 · PreprintNeuroscience

Recording large-scale, cellular-resolution neuronal activity from freely-moving mice

Aniruddha Das, Sarah J. Holden, Julie A. Borovicka, Jacob Icardi, Davina Patel, Rushik Patel, Jacob Raber, Hod Dana

This paper introduces a method to record single-cell cortical activity from freely-moving mice using CaMPARI, revealing task-dependent activity patterns in motor and somatosensory cortices.

bioRxiv · Jun 1, 2022 · PreprintNeuroscience