Functional Annotation of Chemical Libraries across Diverse Biological Processes
Jeff S. Piotrowski, Sheena Claire Li, Raamesh Deshpande, Scott W. Simpkins, Justin Nelson, Yoko Yashiroda, Jacqueline M. Barber, Hamid Safizadeh, Erin H. Wilson, Hiroki Okada, Abraham Abera Gebre, Karen Kubo, Nikko P. Torres, Marissa A. LeBlanc, Kerry Andrusiak, , Charles M. Boone
This study develops a yeast-based chemical-genetic screening system to annotate compound functionality across biological processes and identifies compounds with dual modes of action.
Nature Chemical Biology · Jul 24, 2017Peer-reviewedSystems Biology