Author

Nikko P. Torres

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Grant W. BrowniD· 3 shared Brandon HoiD· 2 shared Raphaël Loll‐KrippleberiD· 2 shared Abraham Abera GebreiD· 1 shared Anastasia BaryshnikovaiD· 1 shared Andreas P. CunyiD· 1 shared Brenda AndrewsiD· 1 shared Chad L. MyersiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersSystems Biology

Grant W. BrownORCID

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3 papers

Recent·Most cited

Mec1-Independent Activation of the Rad53 Checkpoint Kinase Revealed by Quantitative Analysis of Protein Localization Dynamics

Brandon Ho, Ethan James Sanford, Raphaël Loll‐Krippleber, Nikko P. Torres, Marcus Bustamante Smolka, Grant W. Brown

The paper identifies Rad53-dependent protein localization changes during replication stress, revealing Mec1-independent activation of Rad53 in yeast.

eLife · May 19, 2023Peer-reviewedGenetics

Phenotypic Heterogeneity in the DNA Replication Stress Response Revealed by Quantitative Protein Dynamics Measurements

Brandon Ho, Raphaël Loll‐Krippleber, Nikko P. Torres, Andreas P. Cuny, Fabian Rudolf, Grant W. Brown

The paper quantifies protein localization dynamics in yeast during DNA replication stress, revealing phenotypic heterogeneity and previously undetected re-localization events.

bioRxiv · Jun 8, 2022 · PreprintSystems Biology

Functional Annotation of Chemical Libraries across Diverse Biological Processes

Jeff S. Piotrowski, Sheena Claire Li, Raamesh Deshpande, Scott W. Simpkins, Justin Nelson, Yoko Yashiroda, Jacqueline M. Barber, Hamid Safizadeh, Erin H. Wilson, Hiroki Okada, Abraham Abera Gebre, Karen Kubo, Nikko P. Torres, Marissa A. LeBlanc, Kerry Andrusiak, , Charles M. Boone

This study develops a yeast-based chemical-genetic screening system to annotate compound functionality across biological processes and identifies compounds with dual modes of action.

Nature Chemical Biology · Jul 24, 2017Peer-reviewedSystems Biology