Author

Jaie Rattle

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Gad M. FrankeliD· 4 shared Joshua L. C. WongiD· 4 shared Julia Sanchez‐GarridoiD· 3 shared Jonathan Bradshaw· 2 shared Connor PrestoniD· 1 shared Étienne MeunieriD· 1 shared Immaculada Margarit Y Ros· 1 shared Karin SantoniiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

Gad M. FrankelORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TraN variants mediate conjugation species specificity of IncA/C, IncH and Acinetobacter baumannii plasmids

Shan He, Sophia David, Jaie Rattle, Julia Sanchez‐Garrido, Wen Wen Low, Joshua L. C. Wong, Konstantinos Beis, Gad M. Frankel

Journal of Bacteriology · Mar 19, 2026Peer-reviewedMicrobiology

The capsule of hypervirulent Klebsiella pneumoniae maintains neutrophils in neutral activation state

Karin Santoni, Joshua L. C. Wong, Jaie Rattle, Étienne Meunier, Gad M. Frankel

This study shows hypervirulent Klebsiella pneumoniae uses its capsule to prevent neutrophil activation, allowing bacterial survival despite immune presence.

bioRxiv · Feb 25, 2026 · PreprintImmunology

citrOgen: a synthesis-free polysaccharide and protein antigen-presentation to antibody-induction platform

Joshua L. C. Wong, Julia Sanchez‐Garrido, Jaie Rattle, Jonathan Bradshaw, Vishwas Mishra, Gad M. Frankel

The paper introduces a platform using Citrobacter rodentium to generate antibodies against bacterial polysaccharides and proteins without requiring purified or synthetic antigens.

Nature Communications · Oct 6, 2025Peer-reviewedMicrobiology

The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats Klebsiella pneumoniae in vivo

Jonathan Bradshaw, Julia Sanchez‐Garrido, Rita Berkachy, Jaie Rattle, Connor Preston, Mariagrazia Pizza, Immaculada Margarit Y Ros, Maria Rosaria Romano, Joshua L. C. Wong, Gad M. Frankel

This paper shows that Klebsiella pneumoniae produces extracellular PNAG in vitro but switches to cell-associated PNAG during lung infection, highlighting its potential as a vaccine antigen.

bioRxiv · Sep 23, 2024 · PreprintMicrobiology