Author
Shan He
Imperial College LondonORCID 0009-0001-0452-9417Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 38 mutual co-author links4 papers
Recent·Most cited
- MicrobiologyJournal of BacteriologyPeer-reviewed
- MicrobiologyNature CommunicationsPeer-reviewed
H pilin cyclisation and pilus biogenesis are promiscuous but electrostatic perturbations impair conjugation efficiency
Shan He, Naito Ishimoto, Joshua L. C. Wong…·Gad M. Frankel
The paper shows that pilin cyclisation and pilus formation are robust to amino acid substitutions, but electrostatic changes impair conjugation efficiency.
2 citationstop 4% - MicrobiologyProceedings of the National Academy of SciencesPeer-reviewed
Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin
Naito Ishimoto, Joshua L. C. Wong, Shan He…·Konstantinos Beis
The paper reports the cryo-EM structure of the H-pilus, revealing its cyclic pilin subunit and explaining its role in conjugation.
8 citations - MicrobiologyNature CommunicationsPeer-reviewed
Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT
Chloe Seddon, Sophia David, Joshua L. C. Wong…·Konstantinos Beis
The paper determines the cryo-EM structure of TraT proteins from plasmids and reveals their evolutionary history, showing independent acquisition by different plasmid backbones.
10 citations