Author

Jakob Freudenberger

German Cancer Research Center

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Axel AbeleiniD· 1 shared Axel LeppertiD· 1 shared Cecilia MörmaniD· 1 shared Dilraj LamaiD· 1 shared Gefei CheniD· 1 shared Hannah OsterholziD· 1 shared Michael LandrehiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiophysics

Axel AbeleinORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintMar 6, 2026

Liquid-liquid phase separation of tau regulates client binding via a conformational relay

Hannah Osterholz, Gefei Chen, Jakob Freudenberger…·Axel Leppert

The paper investigates how tau's liquid-liquid phase separation affects its binding to BRICHOS and tubulin, showing conformational changes regulate these interactions.

DOI 10.64898/2026.01.21.700558

humanproteomics

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