Dilraj Lama

The paper uses mass photometry to study RNA-protein interactions in phase-separated systems, showing RNA promotes tau multimerization and phase re-entry.

The paper demonstrates that sulanemadlin, a stapled peptide inhibitor of MDM2, specifically activates p53 in zebrafish without inducing apoptosis, enabling direct in vivo studies of p53 regulation.

The paper investigates how tau's liquid-liquid phase separation affects its binding to BRICHOS and tubulin, showing conformational changes regulate these interactions.