Author
Karolinska InstitutetORCID 0000-0002-5543-5963Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Agnieszka N. Urbanek, Alexander J. Dear, David Rhodes…·Suman De
This study identifies two distinct amyloid-β intermediates that drive Alzheimer's pathology and shows their suppression reduces plaque burden and improves cognition in mice.
Hannah Osterholz, Gefei Chen, Jakob Freudenberger…·Axel Leppert
The paper investigates how tau's liquid-liquid phase separation affects its binding to BRICHOS and tubulin, showing conformational changes regulate these interactions.
Riccardo Maccioni, Caterina Travisan, Stefania Zerial…·Simone Tambaro
This study shows that SPPL2b affects APP cleavage and has biphasic Aβ-mediated expression in Alzheimer's disease, suggesting it as a potential drug target.