Author

James A Blau

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:perturbation response prediction· 2 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anne BitoniD· 2 shared Michael BoettcheriD· 2 shared Michael T. McManusiD· 2 shared Noah ZaitleniD· 2 shared David WuiD· 1 shared Evan Markegard· 1 shared Frank P. McCormickiD· 1 shared Haopeng WangiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersGenomics

Anne BitonORCID

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2 papers

Recent·Most cited

Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding

Michael Boettcher, Sergio Covarrubias, Anne Biton, James A Blau, Haopeng Wang, Noah Zaitlen, Michael T. McManus

This paper introduces multi-level barcoding to address clonal heterogeneity in pooled genetic screens and demonstrates its ability to resolve cellular heterogeneity issues.

BMC Genomics · Feb 6, 2019Peer-reviewedGenomics

Decoding directional genetic dependencies through orthogonal CRISPR/Cas screens

Michael Boettcher, Ruilin Tian, James A Blau, Evan Markegard, David Wu, Anne Biton, Noah Zaitlen, Frank P. McCormick, Martin Kampmann, Michael T. McManus

The paper introduces an orthogonal CRISPR/Cas screen to systematically activate one gene while knocking out another, enabling the identification and directionality of genetic interactions in human cancer cells.

bioRxiv · Mar 25, 2017 · PreprintMolecular Biology