Author
MRC Prion Unit
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Michael Andrew Quail, Craig H. Corton, James B. Uphill, Jacqueline A. Keane, Yong Gu
The paper tests PCR enzymes for NGS library amplification, finding three that perform well for short reads and one that is best for long fragments.
Microbial Genomics · Apr 5, 2024Peer-reviewedGenomics
Luke W. Bonham, Celeste M M. Karch, Chun Chieh Fan, Chin Hong Tan, Ethan G. Geier, Yunpeng Wang, Natalie Wen, Iris Broce, Yi Li, Matthew J. Barkovich, Raffaele Ferrari, John Hardy, Parastoo Momeni, Günter U. Höglinger, Ulrich Müller, , Murray Grossman
The paper identifies a genetic variant near CXCR4 associated with increased risk for PSP and PD, showing dysregulation of CXCR4 and microglia-related genes in neurodegenerative diseases.
Translational Psychiatry · Apr 11, 2018Peer-reviewedGenetics
B K Kunkle, Benjamin Grenier‐Boley, Rebecca Sims, Joshua C. Bis, Adam Christian Naj, Anne Boland, Maria Vronskaya, Sven J. van der Lee, Alexandre Amlie‐Wolf, Céline Bellenguez, Aura Frizzati, Vincent Antoine Chouraki, Eden R. Martin, Kristel Sleegers, Nandini Badarinarayan, , Clive Holmes
This study performs a large GWAS of Alzheimer's disease, identifies four new risk loci, and highlights pathways involving immunity, lipid metabolism, and APP/Aβ processing.
bioRxiv · Apr 5, 2018 · PreprintGenetics
Iris Broce, Celeste M M. Karch, Natalie Wen, Chun Chieh Fan, Yunpeng Wang, Chin Hong Tan, Naomi Kouri, Owen A. Ross, Günter U. Höglinger, Ulrich Müller, John Hardy, Parastoo Momeni, Christopher Paul Hess, William P. Dillon, Zachary Miller, , John Collinge
This study identifies genetic overlaps between frontotemporal dementia and immune-mediated diseases, finding strong enrichment with rheumatoid arthritis and moderate enrichment with other immune conditions.
PLoS Medicine · Jan 9, 2018Peer-reviewedGenetics