The RNA-binding protein, Rasputin/G3BP, enhances the stability and translation of its target mRNAs
John D. Laver, Jimmy Ly, Jamie K. Winn, Angelo Karaiskakis, Sichun Lin, Kun Nie, Giulia Benic, Nima Jaberi-Lashkari, Wen Xi Cao, Alireza Khademi, J. Timothy Westwood, Sachdev S. Sidhu, Quaid Morris, Stéphane Angers, Craig A. Smibert, Howard D. Lipshitz
This study identifies RIN/G3BP-bound mRNAs in Drosophila and shows they are short, stable, and highly translated, suggesting RIN stabilizes and enhances their translation.
Cell Reports · Mar 1, 2020Peer-reviewedGenomics