The Nucleosome Remodelling and Deacetylation complex restricts Mediator access to enhancers to control transcription
Maria Xenophontos, Nicola Reynolds, Sarah Gharbi, Ewan R Johnstone, Jason Signolet, Robin Floyd, Meryem Ralser, Susanne Bornelöv, Sabine Dietmann, Remco Loos, Paul Bertone, Brian Hendrich
This study shows the NuRD complex regulates enhancer chromatin structure and Mediator access to control transcription during lineage commitment in ES cells.
bioRxiv · Jan 25, 2017 · PreprintMolecular Biology