Author

Meryem Ralser

Wellcome/MRC Cambridge Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Brian HendrichiD· 2 shared Nicola ReynoldsiD· 2 shared Robin FloydiD· 2 shared Sabine DietmanniD· 2 shared Sarah GharbiiD· 2 shared A. Francis Stewart· 1 shared Andreas BeyeriD· 1 shared Andreas LackneriD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Brian HendrichORCID

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Author profile →

3 papers

Recent·Most cited

Cooperative molecular networks drive a mammalian cell state transition

Andreas Lackner, Robert Sehlke, Marius Garmhausen, Giuliano Giuseppe Stirparo, Michelle Huth, Fabian Titz-Teixeira, Petra van der Lelij, Julia Ramesmayer, Henry Fabian Thomas, Meryem Ralser, Laura Santini, Mihail Sarov, A. Francis Stewart, Austin Smith, Andreas Beyer, Martin Leeb

The paper identifies molecular networks driving the transition from naive to formative pluripotency in mammalian cells using genetic and transcriptomic analyses.

bioRxiv · Mar 23, 2020 · PreprintSystems Biology

Subunit redundancy within the NuRD complex ensures fidelity of ES cell lineage commitment

Thomas Burgold, Michael Barber, Susan L. Kloet, Julie Cramard, Sarah Gharbi, Robin Floyd, Masaki Kinoshita, Meryem Ralser, Michiel Vermeulen, Nicola Reynolds, Sabine Dietmann, Brian Hendrich

The paper shows that MTA proteins in ES cell NuRD complex are functionally redundant, and NuRD is essential for maintaining differentiation trajectory during early lineage commitment.

The EMBO Journal · Apr 29, 2019Peer-reviewedDevelopmental Biology

The Nucleosome Remodelling and Deacetylation complex restricts Mediator access to enhancers to control transcription

Maria Xenophontos, Nicola Reynolds, Sarah Gharbi, Ewan R Johnstone, Jason Signolet, Robin Floyd, Meryem Ralser, Susanne Bornelöv, Sabine Dietmann, Remco Loos, Paul Bertone, Brian Hendrich

This study shows the NuRD complex regulates enhancer chromatin structure and Mediator access to control transcription during lineage commitment in ES cells.

bioRxiv · Jan 25, 2017 · PreprintMolecular Biology