A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival
Jacob Duran, Jay E Salinas, Rui Ping Wheaton, Suttinee Poolsup, Lee Allers, Mónica Rosas‐Lemus, Li Chen, Qiuying Cheng, Jing Pu, Michelle Salemi, Brett S. Phinney, Pavel V. Ivanov, Alf Håkon Lystad, Kiran Bhaskar, Jaya Rajaiya, , Jingyue Jia
The paper identifies a calcium-dependent pathway involving ALIX that links lysosomal damage to stress granule formation, promoting cell survival in response to various stressors.
The EMBO Journal · Nov 12, 2024Peer-reviewedCell Biology