The Integrator complex cleaves nascent mRNAs to attenuate transcription
Deirdre C. Tatomer, Nathan D. Elrod, Dongming Liang, Mei‐Sheng Xiao, Jeffrey Z. Jiang, Michael Jonathan, Kai-Lieh Huang, Eric J. Wagner, Sara R. Cherry, Jeremy E. Wilusz
The paper identifies the Integrator complex as a regulator of transcription by cleaving nascent mRNAs, revealing its role in attenuating gene expression during copper stress.
bioRxiv · Aug 28, 2019Molecular Biology