Nathan D. Elrod

This study identifies novel Pumilio target genes and reveals how Pumilio and CCR4-NOT deadenylase regulate mRNA stability and translation efficiency in Drosophila.

This study identifies RBFOX2's role in maintaining alternative polyadenylation and mitochondrial health in rat myoblasts, linking it to heart disease pathology.

The paper identifies inositol hexakisphosphate (IP6) as a critical regulator of Integrator assembly and function in Drosophila and humans.

The paper identifies an atlas of 3QTLs associated with alternative polyadenylation across 46 tissues, showing they explain 16.1% of trait-associated variants and contribute to disease independently of gene expression.

This study identifies how PUM1 and PUM2 regulate gene expression by interacting with the CCR4-NOT complex and DCP2 to repress mRNA decay.

The paper shows that partial loss of CFIm25, a protein regulated by NUDT21, causes learning deficits and molecular changes in neurons.

The paper shows the Integrator complex destabilizes paused RNA polymerase II at promoters, leading to termination of non-productive transcription.

The paper identifies the Integrator complex as a regulator of transcription by cleaving nascent mRNAs, revealing its role in attenuating gene expression during copper stress.