Sara R. Cherry

This study shows Jamestown Canyon virus adapts to mosquito cells through multiple M segment mutations, enhancing replication efficiency but no single mutation fully reproduces the natural adaptation phenotype.

The paper identifies soluble sialic acid as a conserved biomarker of inflammation through metabolomics in mouse tissues and cultured macrophages.

This study develops a microphysiological model of the human oral cavity to study host-microbe interactions during bacterial, fungal, and viral infections.

The paper identifies a novel SARS-CoV-2-derived circular RNA, circ7b8N, which modulates host gene expression and is detectable in clinical samples, suggesting a role in host-pathogen interactions.

This study infects rhesus macaques with a recent ONNV clinical isolate, demonstrating viremia, immune activation, and clinical disease features similar to human infection.

This study identifies an alternative splicing mechanism in IRF7 that generates a protein isoform with enhanced transcriptional activity, leading to increased resistance to viral infection.

This study investigates how obesity affects the long-term effects of SARS-CoV-2 infection in nonhuman primates, finding persistent changes in multiple parameters in most animals.

The paper shows that alternative splicing contributes to gene disruption in AML, increasing the number of patients with functional gene loss beyond what is detected by mutations alone.

The paper identifies the Integrator complex as a regulator of transcription by cleaving nascent mRNAs, revealing its role in attenuating gene expression during copper stress.