Author

Liqiong Ou

Peking UniversityORCID 0000-0003-4962-7173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jianhang Yin· 2 shared Jiazhi HuiD· 2 shared Changchang XiniD· 1 shared Chenjian LiiD· 1 shared Jiasheng LiiD· 1 shared Jinchun WuiD· 1 shared Mengzhu LiuiD· 1 shared Shaopeng Yuan· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jianhang Yin

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2 papers

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedMar 18, 2026

Self-inactivating AAV-CRISPR at different ages enables sustained amelioration of Huntington's disease deficits in BAC226Q mice

Yuanyi Dai, Zuliayeti Abudujielili, Yunyi Ding…·Chenjian Li

Self-inactivating CRISPR targeting mutant huntingtin in HD mice achieved long-term rescue of neural pathology, motor deficits, weight loss and survival.

3 citationstop 3%

mouseexperimental assay

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GenomicsbioRxivPreprintJul 19, 2023

Transfer of mitochondrial DNA into the nuclear genome during gene editing

Jinchun Wu, Yang Liu, Liqiong Ou…·Jiazhi Hu

This study shows that genome editing can transfer mitochondrial DNA into the nuclear genome, and provides a solution using TREX1 or TREX2 exonucleases.

DOI 10.1101/2023.07.19.549443

humanmouse

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