Author

Jianhua Yu

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aaron J. LongworthiD· 1 shared Ahmed Mohyeldin· 1 shared Altaf MohammediD· 1 shared Bang H. HoangiD· 1 shared Bin Su· 1 shared Bo Wang· 1 shared Chan Xu· 1 shared Chang LiuiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Aaron J. LongworthORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Restoration of deficient IL-15 signaling enhances innate lymphoid cell immunity in brain metastasis

Timothy P McMullen, Pascal Naef, Erika Zagni, Lei Tian, Eva Zhao, Noah Wechter, Aaron J. Longworth, Isam Adam, Jacob Insua‐Rodríguez, Hannah Savage, Isaac Hur, Sophia A. Garcia, Dennis Ma, Michael H Liew, Sharmila Mallya, , Devon A. Lawson

This study shows that restoring IL-15 signaling enhances group 1 ILCs' anti-tumor activity in brain metastasis, reducing tumor burden through improved cytotoxicity and tissue residency.

bioRxiv · Oct 10, 2026 · PreprintImmunology

The Establishment of Prostate-specific, SKP2 Humanized Mice by CRISPR Knock-in Method Reveals Neoplastic Initiation and Microenvironmental Reprogramming

Liankun Song, Yurong Song, Vyvyan Nguyen, Shan Xu, Bang H. Hoang, Altaf Mohammed, Robert H. Shoemaker, Jianhua Yu, Edward Uchio, Xiaolin Zi

This study establishes a prostate-specific hSKP2 knock-in mouse model to investigate SKP2's role in cancer initiation and microenvironmental changes.

Oncogene · Aug 1, 2026Peer-reviewedCancer Biology

Decoding Immune Reconstitution Failure in People Living with HIV through Single-cell Genomics

Yuxing Wang, Shichen Yang, Yue Yuan, Mingli Zhu, Jun Chen, Yong Bai, Shanshan Duan, Xuyang Shi, Tianyu Lu, Zongxing Yang, Zhuoli Huang, Dingyan Yan, Yuhui Zheng, Xuanchi Zhou, Jun Yan, , Chuanyu Liu

This study uses single-cell multi-omics to analyze immune reconstitution failure in HIV patients, identifying genetic and epigenetic factors and developing a predictive model.

bioRxiv · May 23, 2026 · PreprintGenetics