Author

Jianjian Guo

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Organism:human· 1

Frequent Co-Authors

Adan Codina· 1 shared Ava Albis· 1 shared Avnika PantiD· 1 shared Dylan T. TomaresiD· 1 shared Guanghong Luo· 1 shared Jie WuiD· 1 shared Jonathan Joon-Young ParkiD· 1 shared K. SatohiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenomics

Adan Codina

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mast cell extracellular granules are bioactive condensates driven by heparin and polyamine

Yiwei Xiong, Dylan T. Tomares, JianJian Guo, K. Satoh, Longhui Zeng, Yuan Tian, Maohan Su, Ava Albis, Avnika Pant, Rohit V. Pappu, Xiaolei Su

This study identifies mast cell extracellular granules as bioactive condensates formed by heparin and polyamines, enhancing enzymatic activity and cytokine bioactivity.

bioRxiv · Dec 26, 2025 · PreprintCell Biology

Double knockout CRISPR screen in cancer resistance to T cell cytotoxicity

Jonathan Joon-Young Park, Adan Codina, Lupeng Ye, Stanley Z. Lam, Jianjian Guo, Paul R. Clark, Xiaoyu Zhou, Lei Peng, Sidi Chen

The paper identifies genetic interactions between cancer mutations and immune resistance genes using a CRISPR double knockout screen, revealing potential targets for existing drugs.

Journal of Hematology & Oncology · Dec 1, 2022Peer-reviewedGenomics

Lack of dcf1 leads to neuronal migration delay, axonal swollen and autism-related deficits

Ruili Feng, Yanlu Chen, Yangyang Sun, Guanghong Luo, Jianjian Guo, Qiang Liu, Jie Wu, Xiang-Chun Ju, Tieqiao Wen

This study shows that DCF1 deletion in mice causes neuronal migration delay, axonal swelling, and ASD-like behaviors through ERK signaling dysregulation.

bioRxiv · Feb 20, 2020 · PreprintNeuroscience