Author

Jie Zhou

BGI Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Chang LiuiD· 1 shared Chenfei WangiD· 1 shared Chengxin Shen· 1 shared Chenzhang Ji· 1 shared Chi Chen· 1 shared Chuanyu LiuiD· 1 shared Cong LuiD· 1 shared Congfeng Xu· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Chang LiuORCID

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Author profile →

4 papers

Recent·Most cited

Natural killer cell migration in HIV-infected individuals is inhibited by impairment of HIF-1alpha-mediated glycolysis

Xiaowen Yu, Jie Zhou, Jie Lei, Hongchi Ge, Zining Zhang, Yajing Fu, Xiaoxu Han, Qinghai Hu, Haibo Ding, Wenqing Geng, Hong Shang, Yongjun Jiang

This study identifies that impaired NK cell migration in HIV-infected individuals is due to TIGIT inhibiting HIF-1-mediated glycolysis through PI3K/AKT/mTORC1 or ERK pathways.

Cell Death and Disease · Nov 7, 2025Peer-reviewedImmunology

CTHRC1 is a new therapeutic target and serum diagnostic biomarker for aortic dissection

Jiaxin Chen, Luzhang Ji, Jing Lü, Peng Wei, Yihao Li, Hui Huang, Chi Chen, Qiyong Li, Xin Dong, Tao Yu, Jin Tan, Guofang Xia, Jing Lin, Xianjing Wei, Ying Zhang, , Xiaoqing Wang

This paper identifies CTHRC1 as a therapeutic target and serum biomarker for aortic dissection, showing it regulates VSMC phenotype and aortic integrity via the ERK1/2 pathway.

bioRxiv · Apr 19, 2025 · PreprintCell Biology

Deciphering the Cell-Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish

Xiumei Lin, Xue Wang, Chang Liu, Chuanyu Liu, Tao Zeng, Ziqi Yuan, Meidi Hu, Rong Xiang, Kaichen Zhao, Jie Zhou, Shichen Yang, Yang Wang, Kaifeng Meng, Hui Zhu Wang, Guangli He, , Liang Chen

The paper uses single-cell long-read transcriptome sequencing to study transcript diversity and alternative splicing in zebrafish embryos, identifying cell populations with distinct splicing regulations during early development.

bioRxiv · Sep 8, 2024 · PreprintDevelopmental Biology

A foundation model for generalizable cancer diagnosis and survival prediction from histopathological images

Zhaochang Yang, Ting Wei, Ying Liang, Xin Yuan, RuiTian Gao, Yujia Xia, Jie Zhou, Yue Zhang, Zhangsheng Yu

This paper introduces BEPH, a lightweight foundation model for cancer diagnosis and survival prediction from histopathological images, showing improved performance over existing models with limited data.

bioRxiv · May 16, 2024Pathology