Xiumei Lin

This study uses single-cell multi-omics to analyze transcript isoform and immune repertoire changes in aging human immune cells, identifying age-related molecular features in T cells and B cells.

This study uses single-cell multi-omics to analyze immune reconstitution failure in HIV patients, identifying genetic and epigenetic factors and developing a predictive model.

The paper uses single-cell multiomics to study gene regulatory programs in mouse embryonic skin, identifying cis-regulatory elements and transcription factors involved in development.

This study uses multi-omics data to analyze immune and metabolic changes in mountain climbers during acclimatization and extreme altitude exposure.

The paper uses single-cell long-read transcriptome sequencing to study transcript diversity and alternative splicing in zebrafish embryos, identifying cell populations with distinct splicing regulations during early development.

The paper constructs a 3D spatiotemporal multi-omics atlas of Drosophila development, revealing gene regulatory networks and cell type dynamics across embryogenesis to metamorphosis.

This study maps gene expression and developmental trajectories in zebrafish embryos using Stereo-seq and scRNA-seq, identifying spatial gene modules and signaling interactions.

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

This study creates the first single-cell brain atlas of domestic pigs, identifies cell types and their spatial distribution, and compares them with other species to reveal evolutionary and disease-related insights.